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The UCSF Breast Cancer Center of Excellence was established by Dr. Laura Esserman to foster a cancer care system that tailors treatment to patient preferences and biology, based on medical evidence and clinical performance. The center collaborates with universities, government agencies, private foundations, and companies around the world to develop information systems designed to support this model of cancer care. A guiding principle of the center is to make these innovations available for use as open source software or open content in order to minimize barriers to adoption.

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